Title: CLINICO-THERAPEUTIC MANAGEMENT OF HEPATIC JAUNDICE IN INDIGENOUS CATTLE

Authors: HA Shaikh, AU Bhikane, RK Jadhav and SG Chavhan

Source: Ruminant Science (2018)-7(2):305-310.

Cite this reference as: Shaikh HA, Bhikane AU, Jadhav RK and Chavhan SG (2018). Clinico-therapeutic management of hepatic jaundice in indigenous cattle. Ruminant Science 7(2):305-310.

Abstract

Thirty-seven clinical cases of hepatic jaundice in cattle showing clinical signs viz., anorexia, absence of water intake, emaciation, rumen stasis with passage of hard pelleted feces, icteric to congested icteric mucosae, dark yellow to amber colored urine and necrotic skin with significant increase in total, direct and indirect bilirubin, blood urea nitrogen and creatinine compared to healthy cattle were treated with two treatment protocols to study the comparative efficacy of amoxicillin-cloxacillin and enrofloxacin. All the clinical cases were divided in two groups, Group I (n=25) were treated with amoxicillin-cloxacillin (10 mg/kg) and Group II (n=12) were treated with enrofloxacin (5 mg/kg). Cattle in both the groups were treated with supportive treatment of dextrose @ 25 ml/kg IV in 2 divided doses for 7 to 10 days or till recovery, vitamin B complex with herbal liver tonic (Tab. Livorak®) orally daily for 15-20 days, Inj. chlorepheniramine maleate (IM) in cases showing signs of pruritus due to hepatogenous photosensitization and herbal laxative (Protolax®) for treatment of constipation. The corticosteroids were given to stimulate appetite and to prevent hepatic fibrosis. The overall clinical recovery rate was higher (80%) in-group I cattle treated with amoxicillin-cloxacillin compared to group II cattle treated with enrofloxacin (58.33%). However, recovery period in both the groups showed non-significant variation (Group I-16.05±1.21 and Group II-16.00±1.11 days).

References

Azeemi Tawheed Ali, Zameer  Mohammad and Rahman Gul (2013). Incidences of theileria and babesia in nangrahar province of Afghanistan. Ruminant Science 2(2):145-147.

Betjes MG and Bajema L (2006). The pathology of jaundice related renal insufficieny-cholemic nephrosis revisited. Journal of Nephrology 19(2):229-233.

Bhikane AU, Ghoke SS, Masare PS, Sayed AM and Awaz KB (2010). Clinical assessment and treatment schedule for hepatitis in bovines-A clinical study. Intas Polivet 11(2):241-243.

Conn HO and Bircher (1988). Hepatic Encephalopathy Management with Lactulose and Related Carbohydrates. East Lensing, MI, Medi-Ed Press.

Dhillon KS and Paul BS (1971). Clinical studies of Lantana camara L. poisoning in buffalo calves with special reference to its effects on rumen motility. Indian Journal of Animal Sciences 41:945-948.

Feldman BF (1980). Clinical pathology of the liver. In: Current Veterinary Therapy VII. Eds: RW Kirk. WB Saunders, Philadelphia. pp 875-85.

Hess PR and Bunch SE (2000). Diagnostic approach to hepatobiliary diseases. In: Kirk’s Current Veterinary Therapy-Small Animal Practice. XIII Edn, WB Saunders. pp 659-63.

Kellerman TS and Coetzer JAW (1985). Hepatogenous photosensitivity diseases in South Africa. Onderstepoort Journal of Veterinary Research 52:157-173.

Langer Anil, Rani Sunita, Sharma Sonia, Bhojani Rakesh and Soren Sanjhli (2014). Hemato-biochemical alteration in cows naturally infected with theileria. Ruminant Science 3(1):59-62.

Radostits OM, Gay CC, Hinchclif KW and Constable PD (2010). Veterinary Medicine. 10th Edn, Saunder Elsevier, Philadelphia. USA, p 383.

Raguvaran R, Kundave VR, Aishwarya L and Mondal DB (2016). Therapeutic management of tropical theileriosis in cross bred calf. Ruminant Science 5(1):99-100.

Robson S (2007). Photosensitization in stock. Primefacts, p 449.

Rothuizen J and Meyer HP (2000). History, physical examination and signs of liver disease. In: Textbook of Veterinary Internal Medicine. 5th Edn, Eds: SJ Ettinger and EC Fedman. WB Saunders, Philadelphia, pp 1272-1277.

Saritha G, Haritha GS and Nalini Kumari K (2016). Clinico therapeutic management of hepatogenous photosensitization in cattle. Ruminant Science 5(1):87-89.

Sharma J and Wadhwa DR (2009). Clinic-therapeutic studies on lantana toxicosis in cattle in Kangara valley of Himachal Pradesh. Indian Journal of Veterinary Medicine 29(1):23-26.

Sharma Rinku, Kumar R, Ma Gorakhl, Patil RD , Kumar P, Singh B and Bhar R (2017). Association of lantadenes contents and Lantana camara weed toxicity in ruminants of Himachal Pradesh, India. Ruminant Science 6(2):289-292.

Snedecor GW and Cochran WG (1994). Statistical Methods. 8th Edn, Iowa State University Press, Ames, USA.

Soulsby EJL (1982). Helminths, Arthropods and Protozoa of Domesticated Animals. 7th Edn, Bailliere Tindall and Cassel. Ltd. London. pp 707-715.

Stephen RM and Williams R (2003). Jaundice. Oxford Press.