Genetic variants in exon 4 region of FABP3 gene in relation to milk production traits in Sahiwal and Karan fries cattle

Title: Genetic variants in exon 4 region of FABP3 gene in relation to milk production traits in Sahiwal and Karan fries cattle

Authors: Alok Kumar Yadav and Anupama Mukherjee

Source: Ruminant Science (2018)-7(2):189-198.

Cite this reference as: Yadav AK and Mukherjee Anupama (2018). Genetic variants in exon 4 region of FABP3 gene in relation to milk production traits in Sahiwal and Karan Fries cattle. Ruminant Science 7(2): 189-198.

Abstract

The present study pertained to records on milk production and milk constituents of 100 Sahiwal cattle and 115 Karan Fries cattle. The data collected over a period of 2004 to 2016 from Animal Genetics and Breeding Division of ICAR-National Dairy Research Institute, Karnal Haryana. In Sahiwal SNP at position T61045G was highly (p<0.01) associated with FL305DPY and non significant for FL305DMY, FLTMY, FL305 DFY, FL305DSNFY and FL305DPY. The mean±SE of GG genotype for FL305DMY, FLTMY, FL305DFY, FL305DSNFY, FL305DPY were 1794.2±11.0, 2009.7±11.2, 100.18±0.46, 154.82±0.12 and 44.54±0.05 respectively and for TG genotypes were found to be 1802.50±15.5, 1982.70±15.8, 100.73±0.66, 154.63±0.17 and 43.94±0.08 respectively. TT genotypes had the respective values of 1829.30±11.0, 2025.90±11.2, 100.30±0.46, 155.09±0.12 and 43.24±0.05. Homozygous (TT) genotype was superior for FL305DMY, FLTMY, FL305DSNFY traits and Heterozygous (TG) genotype was superior for FL305DFY and homozygous (GG) genotype was superior for FL305DPY traits. In Karan Fries SNP at position T60810C was highly (p<0.01) associated with FL305DMY, FLTMY, FL305DSNFY and FL305DPY and non significantly with FL305DFY. The mean±SE of TT genotype for FL305DMY, FLTMY, FL305DFY, FL305DSNFY, FL305DPY were 3490.69±5.86, 4510.45±8.86, 131.72±4.40, 277.83±0.06 and 113.04±0.05 respectively and for CT genotypes the respective values were 3598.05±8.86, 4617.81±8.86, 144.12±6.66, 278.82±0.09, 114.19±0.08. Heterozygous CT genotype was superior for all traits. In Karan Fries, SNP at position T61170C are highly (p<0.01) associated with FL305DMY, FLTMY, FL305DSNFY and FL305DPY and non significantly with FL305 DFY. The mean±SE of CC genotype for FL305DMY, FLTMY, FL305DFY, FL305DSNFY, FL305DPY were found to be 3582.21±7.10, 4601.97±7.10, 144.02±5.53, 278.69±0.07 and 114.01±0.07, respectively and for TT genotype the respective values were 3478.09±6.23, 4497.85±6.23, 128.93±4.85, 277.70±0.06, 112.91±0.06. CC genotype was superior for all traits in present study.

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