28-Title: Evaluation of general health status and deworming as determinants in the CCHFV seroprevalence in animals in Madhya Pradesh
Authors: Bhawana Rani, Kashyap Yadav, BS Yashavanth, Aniket Sanyal, HV Murugkar and PN Gandhale
Source: Ruminant Science (2023)-12(2):329-333.

Abstract

How to cite this manuscript: Rani Bhawana, Yadav Kashyap, Yashavanth BS, Sanyal Aniket, Murugkar HV and Gandhale PN (2023). Evaluation of general health status and deworming as determinants in the CCHFV seroprevalence in animals in Madhya Pradesh. Ruminant Science 12(2):329-333.
Abstract
Crimean-Congo Hemorrhagic Fever is a potentially fatal tick-borne zoonotic viral disease of humans wherein animals play a very crucial role in virus ecology. Active CCHF serosurveillance was conducted in bovines as well as small ruminants (sheep and goats) from five districts of Madhya Pradesh, India to determine the prevalence of CCHFV antibodies and the influence of General health status (GHS) and deworming on its prevalence. A total of 694 serum samples comprising 444 and 250 sera from bovines and sheep/goats respectively, were collected randomly from the five districts. The district-wise prevalence reported was Barwani (20.59%) >Shivpuri (14.85%) >Jhabua (12.66%) >Harda (10%) >1.96% in Sehore. The animal population tested as a whole had seropositivity of 9.65% (95% CI 7.45-11.85) with higher seropositivity of 12.16% (95% CI 9.12-15.2) in bovines compared to the 5.20% (95% CI 2.44-7.95) in sheep/goat. Bovines without deworming had a higher seroprevalence of 16.22 (95% CI 11.36-21.06) than that of with deworming (8.56% 95% CI 4.51-11.69). Likewise, bovines with good GHS had a higher prevalence of antibodies (13.99%, 95% CI 8.30-19.67) than that with fair GHS (11.63%, 95% CI 7.72-14.87). Similarly, in Sheep/goats, no CCHFV antibodies were detected in animals with deworming, however, seropositivity of 6.63% was observed in animals without deworming. The statistical analysis revealed that CCHFV seroprevalence in bovines (p value-0.013) as well as in the whole studied animal population (p value-0.020) was dependent on deworming. However, no association could be found between the CCHF seroprevalence and deworming in the case of sheep/goats. This was the first attempt to determine if GHS and deworming play any role in CCHFV prevalence in animals.
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